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 PRS Custom 24 in Santana Yellow 10 Top Brand NEW  US $3,055.00
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 FENDER® 51 TELE P BASS BRIDGE PICKUP COVER SET 2 US $21.89
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PRS Custom 24 in Santana Yellow 10 Top Brand NEW US $3,055.00
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FENDER® 51 TELE P BASS BRIDGE PICKUP COVER SET 2 US $21.89
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FENDER® 51 TELE PRECISION P BASS BRIDGE COVER CHROME US $10.39
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NEW Genuine Fender SCN Pickup Mounting Chrome Screws US $6.99
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BRAND NEW Genuine Fender Blues Junior JR Amp COVER US $16.50
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BRAND NEW Genuine Gretsch GOLD Syncro Sonic Bridge US $117.99
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 ESP ltd F254 US $489.00
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 WIRING Kit Chrome Cream Toggle OutJack VOL VOL TONE TONE Free US Ship Guitar US $18.25
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 6 inline Locking Guitar Tuners Tuning Keys Gold NEW US $31.45
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 1956 gibson les paul special TV finish NMno issues NICE AS YOULL SEE US $10,995.00
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 PRS Santana SE US $550.00
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 ToneShaper for Tele Bridge Humbucker 5 Way Switch US $114.99
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 Harmonia 4 4 Size 41 Acoustic Guitar Package Natural US $109.00
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 Guitar Semi Hollow body set neck US $219.00
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 EMG 60 Chrome Active Humbucker PU Chrome US $119.00
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 EMG EMG SPC Strat Presence Control US $47.00
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 MIJ Fender Custom Shack Custom ElectronicsOther Upgrades US $399.95
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 Set Of Two 7 String Pickups US $24.99
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 New Gibson Epiphone Les Paul Black Beauty 3 Electric Guitar Sell Price Reduced US $749.00
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What's a great electric guitar pickup set-up for varied styles of playing?
I don't know the exact names of the pickups, but my friend Alex uses two clear-sounding pickups and one distort/fuzz pickup so he can play cleanly and distorted and they sound great, is there a better setup than this?
Pickups don't distort in and of themselves - some just tend to sound better distorted than others, I suppose. I think you may be talking about single-coil pickups? It's kinda hard to say from the information you're giving.
The most popular pickup combination in the world is the Seymour Duncan '59 in the neck and JB in the bridge. These are humbuckers. They are overall rather trebly, and the JB has a decent combination of higher output and overall clarity that tends to be pretty versatile.
I think my current setup is pretty versatile, but it doesn't favor metal as well as others... that would be the Seymour Duncan Alnico II Pro in the neck and Alternative 8 in the bridge. Slash uses Alnico II Pro's in his guitar, and gets a lot of his distinctive sound from them. The Alt 8 is a good complimentary pickup for it - both are a little more warm and round with a bit of chime/sparkle on the top. The Alt 8 is based on the JB, but has a tighter low end, so is better for rhythm, and less treble, so you don't have that "ice-pick in the brain" syndrome.
I dunno, I don't really want to go much farther and confuse you or point you down the wrong direction. Even with single-coils there are a lot of different options, so I don't want to have an answer that just throws the kitchen sink at you, because that would be a long answer that would probably just confuse you more....
Saul